Isoproturon (34123-59-6)

Isoproturon (34123-59-6)

Use Industrial mass production

Alias 3-(4-Isopropyl*phenyl)-1;Isoproturon;3-(4-Isopropyl*phenyl)-1,1-dimethylurea;N,N-dimethyl- N'-[4-(1-methylethyl)phenyl]urea; isoproturon powder; N-4-isopropyl*phenyl-N',N'-dimethylurea; 3-para - Cumyl-1,1-dimethylurea; isoproturon WP

Purity 99%

Specification 25kg/drum

Molecular formula isoproturon

Product English name Isoproturon

CAS: 34123-59-6

Chinese alias: 3-(4-isopropyl*phenyl)-1; isoproton; 3-(4-isopropyl*phenyl)-1,1-dimethylurea; N,N-dimethylurea base-N'-[4-(1-methylethyl)phenyl]urea; isoproturon powder; N-4-isopropyl*phenyl-N',N'-dimethylurea;3 - p-cumyl-1,1-dimethylurea; isoproturon wettable powder

English name: Isoproturon

Properties: melting point; 158° boiling point; 345.15°C (rough estimate) density; 1.0310 (rough estimate) refractive index; 1.4760 (estimate) flash point; 100 °C storage conditions; APPROX 4℃ maximum wavelength (λmax) 240nm (H2O)(lit.) Merck;14,5218 CAS Database 34123-59-6(CAS DataBase Reference) NIST Chemical Substance Information Urea, n,n-dimethyl-n'-[4-(1-methylethyl)phenyl]- (34123-59-6) EPA Chemical Substance Information Urea, N,N-dimethyl-N'-[4-(1-methylethyl)phenyl]-(34123-59-6)

Uses: Toxicity: The acute oral LD50 of male rats is 1800mg/kg, and that of females is 2400mg/kg; the toxicity test is carried out on rats for more than 30 days, and the no-effect dose is 500mg/kg. Chemical properties; pure product is white odorless powder. m.p.155～156℃, vapor pressure is 3.3×10-6Pa (20℃), soluble in most organic solvents, solubility in water is 17% at room temperature. Stable to light, acid and alkali. Uses; is a selective herbicide use; isoproturon is a selective herbicide, which can be used before and after germination.

For wheat, barley, cotton, corn, soybeans, peas, broad beans, peanuts and other crops to control and control weeds such as maize, crabgrass, wild oats, quinoa, bluegrass, etc. The effect is poor. The recommended dosage is 12-22.5g active ingredient/100m2. Mixed with He Cao Ling, the effect of controlling wild oats and broad-leaved weeds is better. purposes; selective herbicides. Pre-emergence and post-emergence application to control annual grass weeds and broadleaf weeds; this product is a substituted urea herbicide that selectively interferes with weed photosynthesis. Mainly used in wheat, soybeans, cotton, corn and other places to control weeds such as buckwheat, bluegrass crabgrass, wild oats, and foxtail.

Production methods; derived from the reaction between p-isopropyl *benzene isocyanate and dimethylamine. Add 33% dimethylamine aqueous solution to the reaction flask, add water, and when it is cooled to 0-5°C, accelerate stirring, and add p-isopropyl*benzene isocyanate dropwise. The reaction was stirred at 0-5 °C for 2 h, filtered with suction, and the filter cake was recrystallized in acetone to obtain the finished product.

Raw material consumption quota: p-isopropyl*aniline (95%) 980kg/t, dimethylamine (40%) 950kg/t, phosgene (80%) 840kg/t, chlorine 570kg/t. Production method; Isocyanate method for the preparation of cumene isocyanate. Using toluene as a solvent, 4-isopropyl*aniline reacts with phosgene to generate cumene isocyanate. The synthesis of isoproturon is the addition of cumene isocyanate and dimethylamine to generate isoproturon. The feeding process is isocyanate: bis*methylamine=1:1 (mol ratio); dropwise temperature is 15°C, time 20min; reaction temperature is 20～30°C, time 2h.

Using water as solvent, the yield was 95%. The carbamoyl chloride method firstly prepares the preparation of N,N-dimethylcarbamoyl chloride; and then reacts with 4-isopropyl*aniline to synthesize isoproturon. Preparation of p-isopropyltrichloroacetanilide by non-phosgene method After mixing 13.5g (0.1mol) p-isopropyl*aniline and 16.5g (0.1mol) trichloroacetic acid, 14.0g (0.1mol) was added dropwise with stirring Phosphorus trichloride, the temperature was controlled at 100-110 ℃, the constant temperature reaction was completed for 30 minutes, then 100 mL of ice water was added, the solid was collected by suction filtration and washed with water until neutral, and recrystallized with ethanol/water to obtain white crystals with a yield of 91% , mp123～125℃.