3-Chloro-p-toluidine (95-74-9)

3-Chloro-p-toluidine (95-74-9)

Use Industrial mass production

Alias 3-chloro-4-methyl*aniline; 4-amino-2-chloro*toluene; o-chloro-p-aminotoluene; 3-chloro-p-toluidine; 2-chloro-4-aminotoluene; 3-chloro-4- Methyl*aniline; o-chloro-p-toluidine; 2-chloro-4-aminotoluene

Purity 99%

Specification 25kg/drum

Molecular formula 3-Chloro-p-toluidine

Product English Name 3-Chloro-4-methylaniline

CAS: 95-74-9

Chinese alias: 3-chloro-4-methyl*aniline; 4-amino-2-chloro*toluene; o-chloro-p-aminotoluene; 3-chloro-p-toluidine; 2-chloro-4-aminotoluene; 3-chloro- 4-Methyl*aniline; o-chloro-p-toluidine; 2-chloro-4-aminotoluene

English name: 3-Chloro-4-methylaniline

Properties: Melting Point; 25 °C Boiling Point; 237-238 °C(lit.) Density; 1.17 Refractive Index n20/D 1.584(lit.) Flash Point; 212 °F Storage Conditions; 2-8 °C Water Solubility; 1 g /L (20 oC) BRN;636511 Stable. Combustible. Incompatible with strong oxidizing agents, acid chlorides, acids, acid anhydrides, chloroformates, reducing agents. CAS DataBase 95-74-9(CAS DataBase Reference) NIST Chemical Substance Information Benzenamine, 3-chloro-4-methyl-(95-74-9) EPA Chemical Substance Information Benzenamine, 3-chloro-4-methyl-(95-74-9)

Uses: chemical properties; this product is an oily solid at room temperature, mp26℃, bp237～238℃, n20D1.5840, relative density 1.167, fp212℉(100℃), soluble in benzene, alcohol, ether and other solvents . purposes; 3-chloro-4-methyl*aniline is an intermediate of the herbicide chloromerone. Uses; organic synthesis intermediates, used in the production of organic pigment intermediates 2B acid and pesticide chloromelon. Uses; used in the production of organic pigment intermediate 2B acid and pesticide chloromelon herbicide and pharmaceutical intermediates, etc.; obtained by chlorination and reduction of p-nitrotoluene.

1. Chlorination Add nitrotoluene into the reaction pot, heat it to 75°C, put in anhydrous ferric chloride and iodine, stir for 10-20min, start to pass chlorine at 60°C, and keep the chlorination temperature at 55-70°C , when the chloride melting point> 58.5 ℃ does not increase within 20min. Expel the gas, heat up to 80-90°C and keep for 1.5-2h to obtain 2-chloro-4-nitrotoluene with a yield of 98%. 2. Reduction Add the prepared sodium sulfide solution into the reaction pot, add the above 2-chloro-4-nitrotoluene at 70-80°C, reflux for 4h, the temperature is 110±5°C, the purity of amine oil is >98.5%, melting point When > 19 ℃, distillation, the finished product is obtained, and the yield is 90%. If iron powder is used for reduction, the reaction temperature is about 100°C, and the reactant is extracted with toluene. The yield is about 95%. Production method; its preparation method is to add molten 3-chloro-4-methylnitrobenzene and solvent into the autoclave, then under negative pressure, a quantitative catalyst and distilled water are pumped into the autoclave together, and under a certain temperature and pressure Catalytic hydrogenation reaction, then the material is pumped into the storage tank, left to stand for stratification, and the material is rectified in the still to obtain the solvent and the finished product respectively. It can also be reduced with sodium sulfide, add sodium sulfide to the reaction pot, add 3-chloro-4-methylnitrobenzene at 70 ~ 80 ° C, reflux for 4 hours, the temperature is (110 ± 5) ° C, and layer after the reaction. , the finished product is obtained by distillation.